干细胞技术在抗衰老中的应用(5)
[24]Kokai LE，Marra K，Rubin JP.Adipose stem cells： biology and clinical applications for tissue repair and regeneration[J].Transl Res，2014，163(4)：399-408.
[25]Wong SP，Rowley JE，Redpath AN，et al.Pericytes， mesenchymal stem cells and their contributions to tissue repair[J].Pharmacol Ther，2015，151：107-120.
[26]Eom YW，Oh JE，Lee JI，et al.The role of growth factors in maintenance of stemness in bone marrow-derived mesenchymal stem cells[J].Biochem Biophys Res Commun，2014，445(1)：16-22.
, 百拇医药
[27]Sadan O，Shemesh N，Barzilay R.Mesenchymal stem cells induced to secrete neurotrophic factors attenuate quinolinic acid toxicity： A potential therapy for Huntington's disease[J].Exp Neurol，2012，234(2)：417-427.
[28]Burlacu A，Grigorescu G，Rosca AM，et al.Factors secreted by mesenchymal stem cells and endothelial progenitor cells have complementary effects on angiogenesis in vitro[J].Stem Cells Dev，2013，22(4)：643-653.
[29]Pourrajab F，Zarch MB，Yazdi MB，et al.Application of stem cell/growth factor system， as a multimodal therapy approach in regenerative medicine to improve cell therapy yields[J].Int J Cardiol，2014，173(1)：12-19.
, 百拇医药
[30]Beegle J，Lakatos K，Kalomoiris S，et al.Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes， enhances survival and promotes cell retention in vivo[J].Stem Cells，2015，33(6)：1818-1828.
[31]叢秀丽.干细胞与机体衰老的研究进展[J].中国整形外科杂志，2017，28(5)：277-280.
[32]Lavoie JR，Rosu-Myles M.Uncovering the secretes of mesenchymal stem cells[J]. Biochimie，2013，95(12)：2212-2221.
[33]Zhang C，Chen P，Fei Y，et al.Wnt/beta-catenin signaling is critical for dedifferentiation of aged epidermal cells in vivo and in vitro[J].Aging Cell，2012，11(1)：14-23.
, http://www.100md.com
[34]Penga Y，Xuan M，Leunga VYL，et al.Stem cells and aberrant signaling of molecular systems in skin aging[J].Ageing Res Rev，2015，19：8-21.
[35]Bernet JD，Doles JD，Hall JK，et al.p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice[J].Nat Med，2014，20(3)：265-271.
[36]汪润，于艳秋.间充质干细胞及其分泌液抗皮肤光老化作用的研究进展[J].沈阳医学院学报，2017，19(4)：356-363.
[37]Liu S，Wang X，Zhou J，et al.The PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro[J].Aging Cell，2011，10(4)：661-674.
[38]Bader A，Machens HG.Recombinant human erythropoietin plays a pivotal role as a topical stem cell activator to reverse effects of damage to the skin in aging and trauma[J].Rejuvenation Res，2010，13(4)：499-500.
[收稿日期]2018-05-08 [修回日期]2018-07-24
编辑/朱婉蓉, 百拇医药(王勤周 王辉 陈红艳)
[25]Wong SP，Rowley JE，Redpath AN，et al.Pericytes， mesenchymal stem cells and their contributions to tissue repair[J].Pharmacol Ther，2015，151：107-120.
[26]Eom YW，Oh JE，Lee JI，et al.The role of growth factors in maintenance of stemness in bone marrow-derived mesenchymal stem cells[J].Biochem Biophys Res Commun，2014，445(1)：16-22.
, 百拇医药
[27]Sadan O，Shemesh N，Barzilay R.Mesenchymal stem cells induced to secrete neurotrophic factors attenuate quinolinic acid toxicity： A potential therapy for Huntington's disease[J].Exp Neurol，2012，234(2)：417-427.
[28]Burlacu A，Grigorescu G，Rosca AM，et al.Factors secreted by mesenchymal stem cells and endothelial progenitor cells have complementary effects on angiogenesis in vitro[J].Stem Cells Dev，2013，22(4)：643-653.
[29]Pourrajab F，Zarch MB，Yazdi MB，et al.Application of stem cell/growth factor system， as a multimodal therapy approach in regenerative medicine to improve cell therapy yields[J].Int J Cardiol，2014，173(1)：12-19.
, 百拇医药
[30]Beegle J，Lakatos K，Kalomoiris S，et al.Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes， enhances survival and promotes cell retention in vivo[J].Stem Cells，2015，33(6)：1818-1828.
[31]叢秀丽.干细胞与机体衰老的研究进展[J].中国整形外科杂志，2017，28(5)：277-280.
[32]Lavoie JR，Rosu-Myles M.Uncovering the secretes of mesenchymal stem cells[J]. Biochimie，2013，95(12)：2212-2221.
[33]Zhang C，Chen P，Fei Y，et al.Wnt/beta-catenin signaling is critical for dedifferentiation of aged epidermal cells in vivo and in vitro[J].Aging Cell，2012，11(1)：14-23.
, http://www.100md.com
[34]Penga Y，Xuan M，Leunga VYL，et al.Stem cells and aberrant signaling of molecular systems in skin aging[J].Ageing Res Rev，2015，19：8-21.
[35]Bernet JD，Doles JD，Hall JK，et al.p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice[J].Nat Med，2014，20(3)：265-271.
[36]汪润，于艳秋.间充质干细胞及其分泌液抗皮肤光老化作用的研究进展[J].沈阳医学院学报，2017，19(4)：356-363.
[37]Liu S，Wang X，Zhou J，et al.The PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro[J].Aging Cell，2011，10(4)：661-674.
[38]Bader A，Machens HG.Recombinant human erythropoietin plays a pivotal role as a topical stem cell activator to reverse effects of damage to the skin in aging and trauma[J].Rejuvenation Res，2010，13(4)：499-500.
[收稿日期]2018-05-08 [修回日期]2018-07-24
编辑/朱婉蓉, 百拇医药(王勤周 王辉 陈红艳)
参见：首页 > 药学版 > 生命科学 > 干细胞